Focusing on a relatively neglected, but in times of globalization even more important aspect, the influence of cultural characteristics on innovativeness, we apply different econometric models to test for links between cultural tightness and looseness on the one hand, and national innovativeness on the other hand. We find that cultural tightness — in the sense of homogenous and intolerant societies — has a negative link to national innovativeness, while cultural looseness — in the sense of tolerant and diverse societies — displays a positive link to national innovativeness.